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Key words: docking, homology modeling, leprosy, M.leprae, molecular, molecular dynamics, ramachandran plot.

Therefore identification of the novel drug target and potent drug can be helpful in better prevention of the disease. Alter et.al, (2008) Leprosy as a genetic model for susceptibility to common infectious disease, Hum Genet 2. (1999)Health Policy and Planning; 14(2): 89-102, Oxford University Press.

Biologically inspired evolutionary agent systems in dynamic environments.

Diversity-based model reference for genetic algorithms in dynamic environment.

The proposed four ports cylinder was simulated and parameters such as ports sizes, loads and pressures are varied during the simulation.

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